I don't know about the first but the 3rd biggest mistake was quitting cigarettes
Why? You think it'd be better if he was dead already?
Thinking about this seriously, his biggest mistake might have been starting to smoke. The drugs may or may not have helped him creatively, but either way he seems to have got through them with no long term health damages, whereas 60 a day for 40 years is probably what caused his heart attack. My guess is that heart attack effectively ended his career in all but name.
""Looking for love, not sex" -- the tagline of many a troll who doesn't believe they are worthy or capable of sex in its own right, but god, the thought of carrying that sort of middling self-esteem all the way to 36 is disturbing."